Markets
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Luke Kawa

Eli Lilly #1 in GLP-1s after Novo disappointment

Shares of Novo Nordisk are down nearly 20% in early trading on Friday, on track for their worst one-day decline since the infamous Black Monday market crash in 1987.

The GLP-1 drug maker — best known for Ozempic — is getting crushed after saying that users of its experimental obesity shot didn’t lose as much weight as the company had expected. That’s great news for its competitors, namely Eli Lilly, whose Zepbound has not been cleanly unseated by this new Novo treatment (dubbed CagriSema). The drugmakers use different approaches to develop new weight-loss drugs, and right now it looks like Eli Lilly has the upper hand.

This disappointment means that one “overhang on Eli Lilly shares” is diminished, per JPMorgan, with a Citi analyst calling this outcome “nearly a best case-scenario” for Novo’s biggest competitor.

Novo is now negative on the year, while Eli Lilly shares have posted a more than 30% advance.

So in sum: Novo’s patients’ lack of weight loss is Novo’s loss, which is Eli Lilly’s gain.

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Nia Warfield, Luke Kawa
9/26/25
US stocks end a down week with a gain

An up day but a down week for the benchmark US stock index.

Cowboy Riding Bucking Steer
markets
Luke Kawa

Crocs rises on new marketing campaign for HeyDude brand starring Sydney Sweeney


Sydney Sweeney has great... feet?

Shares of Crocs are rising after the footwear company’s HeyDude brand unveiled a new marketing effort starring actress Sydney Sweeney for its Austin Lift shoe line.

Sweeney’s controversial ad campaign for American Eagle spurred a massive jump in the denim maker’s shares, caught the attention of the president, and prompted “an uptick in customer awareness, engagement, and comparable sales,” per American Eagle’s management.

Sweeney was first announced as HeyDude’s global spokesperson in August 2024, and doesn’t seem to have given the brand a major boost so far.

Max Knoblauch
9/26/25

Ford and GM reach 52-week highs as EPA seeks to repeal emissions rules

Shares of Ford and GM are each trading at 52-week highs on Friday, as investors pile into gas-powered US automakers with the looming end of the EV tax credit and the Trump administration’s potential repeal of vehicle emissions standards.

A lobby representing Ford, GM, and nearly all other major automakers has expressed support for the EPA’s proposal to repeal the long-standing endangerment finding that declared greenhouse gases a threat to human life. The finding provides the legal foundation for the EPA to regulate vehicle emissions.

Yesterday, EV giant Tesla urged the Trump administration to keep the standards in place.

Friday afternoon saw Ford shares reach their highest level since July 2024, while GM’s stock hit highs not seen since January 2022.

Citi equity analysts on the key valuation issue facing the market.

Citi’s US market analyst on the key valuation test facing the market

“It kind of comes down to, what inning do you think we are in this AI game?”

Matt Phillips9/26/25
markets
Luke Kawa

GameStop surges as company offers promotions to boost launch of “Pokémon” Mega Evolution set

GameStop is jumping as the company offers promotions to boost interest for today’s North American launch of the Mega Evolution set of the “Pokémon Trading Card Game.”

Options activity is a little more tilted to the bull side than usual. Over the past month, a little less than four calls have changed hands for every put option. As of 10:22 a.m. ET, that ratio is over five to one.

It’s a big day for collectibles fans and gamers alike: beyond the “Pokémon TCG” drop, there are also new collections from “Yu-Gi-Oh!” and “Magic: The Gathering” being released and “EA SPORTS FC 26,” as well.

As we’ve written, “Pokémon” trading cards have been skyrocketing in value, and GameStop’s collectibles business has been accelerating. These are two sides of the same coin.

Mega Gardevoir... here I come!

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