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Pfizer reports earnings beat and boosts guidance as Metsera bid-off heats up

Pfizer reported earnings on Tuesday.

J. Edward Moreno

Pfizer rose in early trading after it reported earnings results on Tuesday that beat Wall Street estimates as the company is embroiled in the middle of a bid-off for obesity biotech Metsera.

The pharmaceutical giant reported adjusted earnings per share of $0.87, compared to the $0.63 analysts polled by FactSet were expecting. The company also narrowed its full-year adjusted profit per share guidance to between $3.00 and $3.15, from between $2.90 and $3.10, which equates to a mild boost to the expected midpoint.

It also reported $16.6 billion in revenue for the quarter, just above the $16.5 billion the Street was penciling in.

The company is down about 7% since the start of the year amid industry-wide headwinds like tariffs as well as its own struggle to secure its next source of revenue growth.

Meanwhile, Pfizer launched a legal battle this week against Novo Nordisk — its Danish competitor and maker of Ozempic — for seeking to intercept its acquisition bid for Metsera, an obesity biotech working on a next-generation GLP-1 drug.

Metsera said on Monday that both Novo and Pfizer upped their bids for the company, but Novo's was still superior to Pfizer’s.

The spat underscores just how much the weight-loss medication race is heating up. Earlier this year, Pfizer scrapped a GLP-1 pill it was developing after data from clinical trails fell short. Novo, while first to the GLP-1 market, is watching Eli Lilly’s drugs eat its lunch.

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Major after-hours block trades on Monday drag down Spotify

Spotify is on pace for its worst trading day since July, with shares down more than 8% on Tuesday afternoon.

Major after-hours block trades Monday appear to be driving negative momentum on Tuesday. At 4:52 p.m. ET Monday, 300,000 shares of Spotify were traded at $508.58, a $152.6 million exodus. That represents about 12% of the average daily trading volume for Spotify over the past 20 sessions.

Less than an hour earlier, just after Monday’s close, 131,757 shares were sold at the same price point. Together, the two trades represent about a $220 million withdrawal from the music streamer.

Spotify is expected to report its fourth-quarter and full-year earnings results a week from Tuesday. This month marks the company’s third US subscription price hike in the past three years.

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Opendoor Technologies jumps on reported “Trump Homes” plan from developers, positive signals on mortgage loan growth

Opendoor Technologies is surging on Tuesday on a double dose of good news: a report that mortgage loan growth is soaring and a potential plan to boost US housing supply.

Speaking on CNBC, Rocket Companies CEO Varun Krishna said his firm is “on track to produce the highest mortgage loan volume and the highest gain on sale in four years.”

Separately, Bloomberg reports that US developers are pursuing a “Trump Homes” plan to build up to 1 million homes (or $250 billion in housing) in a bid to make homeownership more accessible. Shares of Lennar and Taylor Morrison, which are both said to be involved with this program, are up on this report.

The Trump Homes plan is being discussed by developers, and Bloomberg reports that “the administration is not actively considering the plan, a White House official said, speaking on condition of anonymity.”

A more active real estate market is music to the ears of Opendoor bulls. Following its Q3 earnings report, new CEO Kaz Nejatian indicated that his plan to turn around the online real estate company involved a high-volume strategy: buying more homes faster, and quickly flipping them for a small profit. The company has significantly expanded its homebuying footprint to include the entire Lower 48 states.

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Novo expects sales will drop in 2026 amid rising competition

Ozempic maker Novo Nordisk expects annual sales to decline by up to 13% in 2026 despite signs that its new Wegovy pill, the first oral GLP-1 to come to market, is having strong early uptake.

The pharmaceutical giant gave an early look at its outlook for 2026, with complete results scheduled for Wednesday morning. The Danish drugmaker said it expects sales will fall by 5% to 13%.

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Rocket Companies jumps as CEO touts soaring mortgage loan volumes

The US housing market — or at the very least resale activity — is thawing after a long freeze.

Shares of Rocket Companies are soaring on Tuesday after CEO Varun Krishna told CNBC that the firm is “on track to produce the highest mortgage loan volume and the highest gain on sale in four years.” Rocket, he added, was “right there to capitalize” on the drop in mortgage rates.

Per Realtor.com, the share of US homeowners with mortgage rates above 6% now exceeds those with rates below 3%. This points to a diminished “lock-in” effect that dampened resale activity in the postpandemic economy.

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