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Y Combinator: The startup accelerator has an impressive portfolio

Y Combinator: The startup accelerator has an impressive portfolio

Make something people want

Investing in startups is a high-risk business. First you have to get comfortable with the idea that the vast majority of new companies will go broke — then you have to do your best to bet on the ones that don't, which isn't easy.

But Y Combinator makes it look easy.

With a motto of "make something people want" and an unwavering focus on the founders themselves, San Francisco based Y Combinator has now backed more than 3,500 startups since it started in 2005 — and this week it updated its list of "top companies".

Playing the numbers game

Having written more than 3,500 checks, usually for $125k in exchange for 7% of the company (although this changed recently), Y Combinator has spread the risk of early-stage investing, hoping for a few home-runs that can cover the rest of their investments.

We tracked down the data on the 100 most valuable of those companies YC has invested in, estimating that the top 100 alone are worth something north of $600 billion. A lot of that comes from big name successes like Stripe, Airbnb, Reddit and DoorDash - all of which make the top 10 YC-backed companies.

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Ford reportedly in talks to buy hybrid vehicle batteries from Chinese auto giant BYD

Detroit’s Ford and China’s BYD are said to be in ongoing talks to partner on an agreement that would see Ford buy hybrid vehicle batteries from BYD, according to reporting from The Wall Street Journal.

The report comes just days after President Trump toured a Ford factory in Michigan and implied openness to Chinese automakers coming to the US.

“If they want to come in and build a plant... that’s great, I love that,” Trump said on January 13. “Let China come in, let Japan come in.”

Last week, China’s Geely Automobile Holdings said it expects to make an announcement about expanding into the US within the next three years. Chinese carmakers currently face huge tariffs and software restrictions, effectively barring their vehicles from the US.

Ford has doubled down on hybrid vehicles amid high EV costs and the end of federal EV tax credits. The automaker is currently building a battery plant in Michigan where it plans to use tech from Chinese battery maker CATL.

“If they want to come in and build a plant... that’s great, I love that,” Trump said on January 13. “Let China come in, let Japan come in.”

Last week, China’s Geely Automobile Holdings said it expects to make an announcement about expanding into the US within the next three years. Chinese carmakers currently face huge tariffs and software restrictions, effectively barring their vehicles from the US.

Ford has doubled down on hybrid vehicles amid high EV costs and the end of federal EV tax credits. The automaker is currently building a battery plant in Michigan where it plans to use tech from Chinese battery maker CATL.

Still life of Ozempic and Wegovy with weight scale.

Lawsuit alleges Lilly, Novo locked up telehealth to kill compounded GLP-1s

Novo Nordisk CEO Mike Doustdar estimated that around 1.5 million US patients are using compounded versions of the company’s drugs.

Handshake

Big Pharma enters 2026 with an appetite for deals

At the JPMorgan Healthcare Conference, biotechs and Big Pharma signaled they’re primed for M&A this year, after a big year for deals in 2025.

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