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Merck getting merc’d after cutting Gardasil sales to China

Merck & Co. shares are down more than 10% on Tuesday after the drugmaker gave a gloomy guidance for 2025, in part because it will pause shipments of its HPV vaccine to China until at least midyear.

The vaccine giant said it expects to bring in $64.1 billion to $65.6 billion in revenue in 2025, compared to the $67 billion analysts polled by FactSet expected. Merck said it would pause shipments of Gardasil, a vaccine that prevents cancer from HPV, into China beginning in February and going through at least mid-2025. Sales of the vaccine began unexpectedly slumping in China in the second quarter of 2024, which management attributed to an anti-corruption crackdown focusing on the nation’s healthcare industry.

“Like many other companies, we’ve seen increased pressure on discretionary consumer spending, including across the vaccine space more broadly, and demand for Gardasil has not recovered to the level we had expected,” Merck CEO Robert M. Davis told analysts on Tuesday. “As a result, overall channel inventory remains elevated at above-normal levels.”

Gardasil is a key product for Merck, bringing in $8.6 billion of its $64.1 billion in sales for 2024. That shipment pause is another headwind for Gardasil, which already declined in demand compared to 2023.

Meanwhile, vaccine skeptic Robert F. Kennedy Jr. is nearing confirmation as secretary of the Department of Health and Human Services. Kennedy has referred clients to the law firm that’s filed suit against Merck, saying Gardasil has potentially severe adverse effects.

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$1.3M

There’s still plenty of money to be made in brainrot. The top 1,000 Roblox creators earned an average of $1.3 million in 2025 — up 50% from the year prior — according to CEO Dave Baszucki on the company’s fourth-quarter earnings call.

Roblox paid out $1.5 billion to creators last year, meaning its top 1,000 creators took home about 87% of the total pool.

Like other creator economy giants, Roblox rewards its biggest creators for their contributions to user engagement. Creator-made titles like “Grow a Garden” and “Steal a Brainrot” substantially boosted playing time over the course of the year. In September, the company increased its developer exchange rate, or the ratio of in-game currency to cash payout, by 8.5%.

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The new owner of rhode beat estimates for its fiscal third quarter and boosted its guidance for the full year, even as headwinds in the UK and Germany continued.

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Roblox answers Google’s Project Genie, launching the open beta for its “4D” AI creation tool

Roblox on Wednesday launched the open beta of its “4D” AI creation model, less than a week after the launch of Google’s Project Genie, an AI-powered interactive world generator.

The tool allows users to generate interactive objects that can be used in gameplay, such as a drivable car or a flyable plane, as opposed to static 3D objects.

Roblox’s “4D” system relies on rule sets called schemas that create objects out of multiple parts, allowing cars to have a body and movable wheels, for example.

“We expect to soon include schemas that cover the range of thousands of objects in the real world,” the company said.

The move to bring the tool out of early access and into open beta appears to be a response to Google’s Project Genie, which allows users to generate “playable” worlds out of a text or image prompt. Gaming stocks like Roblox, Take-Two, and Unity Software have dropped in the days since Project Genie’s release, though Wall Street analysts largely believe the market reaction to be unjustified, as interactivity through Googles tool is limited.

Roblox’s “4D” system relies on rule sets called schemas that create objects out of multiple parts, allowing cars to have a body and movable wheels, for example.

“We expect to soon include schemas that cover the range of thousands of objects in the real world,” the company said.

The move to bring the tool out of early access and into open beta appears to be a response to Google’s Project Genie, which allows users to generate “playable” worlds out of a text or image prompt. Gaming stocks like Roblox, Take-Two, and Unity Software have dropped in the days since Project Genie’s release, though Wall Street analysts largely believe the market reaction to be unjustified, as interactivity through Googles tool is limited.

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