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Structure Therapeutics posts mid-stage weight-loss pill data in line with Eli Lilly rival

Structure Therapeutics soared in early trading after it reported mid-stage results for its weight-loss pill that were roughly in line with Eli Lilly’s competing product.

The San Francisco-based biotech reported that patients lost roughly 11.3% of their body weight on a lower dose of the pill, aleniglipron, in a mid-stage study. That puts it roughly in line with Lilly’s competing pill, orforglipron, and slightly below Novo Nordisk’s oral Wegovy.

Both Lilly and Novo’s pills are awaiting regulatory approval and are expected to go to market next year. While the weight-loss numbers were encouraging, Structure’s pill did report higher rates of side effects like nausea and vomiting.

Investors have been closely watching drugmakers’ once-daily pills, which could replace the weekly injections currently on the market. While pills tend to be less effective than shots, they are less expensive to manufacture than prefilled injection pens and are more inviting to squeamish patients.

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SpaceX gets a wave of bullish ratings from Wall Street analysts

SpaceX received more than a dozen positive analyst calls on Tuesday — including from major Wall Street banks — as they initiate coverage on Elon Musk’s space and AI company.

SpaceX went public on June 12 at a $2.2 trillion valuation, the largest debut in history. While the company hasn’t yet posted a profit, it seems to have convinced Wall Street that it will get there and grow its valuation on the way.

Of the at least 17 analysts that gave a rating on Tuesday, all but one gave it a “buy” or “outperform” rating. MoffettNathanson was "neutral."

The ratings come as SpaceX joined the Nasdaq 100 index, a benchmark tech-heavy basket of companies that underpins millions of portfolios. The inclusion adds built-in demand for the stock from index funds and ETFs.

Still, SpaceX fell more than 5% on Tuesday amid a broader sell-off, and is currently effectively flat from its opening price of $150 a share.

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