Tempus AI reports Q3 earnings

Tempus AI CEO Eric Lefkofsky (Kevin Dietsch/Getty Images)

Tempus AI dives after-hours despite strong Q3 numbers

The medical diagnostic company, which is developing new AI-driven tests, has at times been a favorite of retail investors.

11/4/25 4:14PM

Tempus AI, a company that captured the attention of retail shareholders and surged to a valuation of more than $15 billion in spite of persistent losses, reported better-than-expected Q3 results after the close of trading on Tuesday.

But investors seemed unimpressed, as the stock — which already fell almost 5% during the regular session — dove another 6.5% after-hours.

The cancer diagnostics and genetic sequencing company, whose CEO we interviewed earlier this year, reported:

Sales of $334.2 million vs. the $328.7 million estimated by 13 Wall Street analysts whose forecasts FactSet tracks.
An adjusted loss per share of $0.11 vs. the $0.17 expected on Wall Street.
Full-year 2025 guidance of ~$1.265 billion vs. the $1.259 billion Wall Street consensus estimate.

Tempus AI went public in June 2024, and was up more than 150% in 2025 through the close of the New York trading session Tuesday.

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