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Eli Lilly tumbles after selling way fewer weight-loss drugs than expected

Shares of Eli Lilly are tumbling after sales of its well-known GLP-1 weight-loss drugs massively undershot Wall Street’s expectations in the fourth quarter.

The company said on Monday that it made approximately $1.9 billion selling Zepbound and $3.5 billion selling Mounjaro in the final quarter of 2024. Analysts polled by FactSet estimated $2.1 billion for Zepbound and $4.4 billion for Mounjaro. 

Both are the same drug (tirzepatide), but Mounjaro is the brand name approved to treat diabetes and Zepbound can be prescribed for a wider range of conditions.

Eli Lilly has struggled to keep up with high demand for its weight-loss drugs. For a chunk of 2024, these drugs were considered in shortage by the US Food and Drug Administration, which allowed copycat compound versions to be sold by companies like Hims & Hers.

“We continued to make progress on our manufacturing build-out, and U.S. supply across all doses of tirzepatide was available throughout Q4,” Eli Lilly CEO David A. Ricks said in a statement. “The rest of our medicines performed within our expectations.”

Ozempic and Wegovy, two other popular GLP-1 weight-loss drugs made by Novo Nordisk, have also faced shortages and have flattened in recent quarters.

Both are the same drug (tirzepatide), but Mounjaro is the brand name approved to treat diabetes and Zepbound can be prescribed for a wider range of conditions.

Eli Lilly has struggled to keep up with high demand for its weight-loss drugs. For a chunk of 2024, these drugs were considered in shortage by the US Food and Drug Administration, which allowed copycat compound versions to be sold by companies like Hims & Hers.

“We continued to make progress on our manufacturing build-out, and U.S. supply across all doses of tirzepatide was available throughout Q4,” Eli Lilly CEO David A. Ricks said in a statement. “The rest of our medicines performed within our expectations.”

Ozempic and Wegovy, two other popular GLP-1 weight-loss drugs made by Novo Nordisk, have also faced shortages and have flattened in recent quarters.

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Delta says the government shutdown will cost it $200 million in Q4

The 43-day government shutdown that ended last month will result in a $200 million ding for Delta Air Lines, the airline said in a filing on Wednesday.

That’s about $100,000 per shutdown-related canceled flight. (Delta previously said it canceled more than 2,000 flights due to FAA flight reductions.) When the company reports its fourth-quarter earnings, the shutdown will lop off about $0.25 per share.

Delta initially stayed calm about the shutdown, with CEO Ed Bastian stating in early October that the company was running smoothly and hadn’t seen any impacts at all. One historically long shutdown later, Delta wasn’t able to remain untouched.

The skies have since cleared, though, and Delta’s filing states that booking growth has “returned to initial expectations following a temporary softening in November.”

Delta’s shares were up over 2% as of Wednesday’s market open.

Delta initially stayed calm about the shutdown, with CEO Ed Bastian stating in early October that the company was running smoothly and hadn’t seen any impacts at all. One historically long shutdown later, Delta wasn’t able to remain untouched.

The skies have since cleared, though, and Delta’s filing states that booking growth has “returned to initial expectations following a temporary softening in November.”

Delta’s shares were up over 2% as of Wednesday’s market open.

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