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Pfizer's big year

Pfizer's big year

It's likely that a good proportion of you reading this newsletter received a Pfizer-BioNTech COVID-19 vaccine at some point in the last 18 months.

For Pfizer, those billions of doses have translated into a record financial performance, with the COVID-19 vaccine (COMIRNATY) bringing in $36.8bn last year — more than any pharmaceutical product has ever sold in a single year.

Incredibly, Pfizer's 2022 is likely to be even better than its 2021, as the company's COVID pill, Paxlovid, hits the market. Indeed, Pfizer announced this week it expects Paxlovid to contribute an incremental $22bn in revenues next year, with the original COVID vaccine good for another $32bn.

The pharmaceutical industry is a unique one, not just because its products can save lives, but because the economics are so unlike any other. Researching, developing and getting drugs approved is an unbelievably long and expensive task. But once achieved, the marginal costs are usually only a fraction of the end sales price — Pfizer incurred just $31bn of direct costs for its $81bn of sales.

Half full, half empty

Whatever your political persuasion, it's easy to reframe these results in a way that pleases. Pandemic profiteering by big pharma? Or the market's solution to a huge problem that the world needed solving? Take your pick.

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Ford reportedly in talks to buy hybrid vehicle batteries from Chinese auto giant BYD

Detroit’s Ford and China’s BYD are said to be in ongoing talks to partner on an agreement that would see Ford buy hybrid vehicle batteries from BYD, according to reporting from The Wall Street Journal.

The report comes just days after President Trump toured a Ford factory in Michigan and implied openness to Chinese automakers coming to the US.

“If they want to come in and build a plant... that’s great, I love that,” Trump said on January 13. “Let China come in, let Japan come in.”

Last week, China’s Geely Automobile Holdings said it expects to make an announcement about expanding into the US within the next three years. Chinese carmakers currently face huge tariffs and software restrictions, effectively barring their vehicles from the US.

Ford has doubled down on hybrid vehicles amid high EV costs and the end of federal EV tax credits. The automaker is currently building a battery plant in Michigan where it plans to use tech from Chinese battery maker CATL.

“If they want to come in and build a plant... that’s great, I love that,” Trump said on January 13. “Let China come in, let Japan come in.”

Last week, China’s Geely Automobile Holdings said it expects to make an announcement about expanding into the US within the next three years. Chinese carmakers currently face huge tariffs and software restrictions, effectively barring their vehicles from the US.

Ford has doubled down on hybrid vehicles amid high EV costs and the end of federal EV tax credits. The automaker is currently building a battery plant in Michigan where it plans to use tech from Chinese battery maker CATL.

Still life of Ozempic and Wegovy with weight scale.

Lawsuit alleges Lilly, Novo locked up telehealth to kill compounded GLP-1s

Novo Nordisk CEO Mike Doustdar estimated that around 1.5 million US patients are using compounded versions of the company’s drugs.

Handshake

Big Pharma enters 2026 with an appetite for deals

At the JPMorgan Healthcare Conference, biotechs and Big Pharma signaled they’re primed for M&A this year, after a big year for deals in 2025.

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