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Wegovy on Hims
A screenshot of Hims & Hers’ website (Sherwood News)

Hims & Hers on track for biggest drop ever after Novo Nordisk ends partnership

Novo said Hims is participating in “illegal mass compounding and deceptive marketing.” The falling out could be a precursor for more legal action.

J. Edward Moreno

Hims & Hers stock plunged, on track for its biggest single-day drop ever, after Novo Nordisk said it was ending its relatively new partnership with the telehealth company, citing concerns about what it called Hims’ “illegal mass compounding and deceptive marketing.”

Shares were recently down 27%.

The move is a sharp reversal from less than two months ago, when the companies announced a partnership on April 29 that allowed Novo’s blockbuster weight-loss drug, Wegovy, to be sold on the Hims & Hers platform. The drugmaker also announced partnerships with two other telehealth companies, Ro and LifeMD, on the same day.

The partnership between parties that had been adversaries when it comes to GLP-1s reflected the drugmaker’s desire to tap into uninsured consumers and the telehealth company’s desire to get name-brand products in its portfolio. When the pact was announced, Hims’ stock jumped 23% in a day.

Novo Nordisk calling Hims’ compounding practices “illegal” is notable considering it has sued dozens of wellness clinics for selling compounded semaglutide. Lawsuits from giant drugmakers are a growing risk for telehealth companies — Eli Lilly has recently sued telehealth providers that continued to sell copies of weight-loss drug Zepbound after the shortage of that drug ended.

Wegovy is still shown as available on its website.

In a Monday afternoon post on X, Hims CEO Andrew Dudum said Novo pressured the company to steer customers away from compounded drugs.

"We refuse to be strong-armed by any pharmaceutical company’s anticompetitive demands that infringe on the independent decision making of providers and limit patient choice," he said.

Hims and its peers had been selling copycat versions of Novo’s weight-loss drugs for about a year while they were allowed to by the government during a shortage. But once that shortage ended in February, their ability to continue selling exact copies became limited.

Novo said it saw the partnership as a way to help Hims patients transition from compounded medications to its branded product. But Hims and others continued to offer compounded versions of Wegovy, marketing them as “personalized.”

Compounded versions of Wegovy can still be sold if a patient requires a modification, such as to remove a nonactive ingredient that they’re allergic to, or if they need a dose that the drugmaker doesn’t manufacture. But Novo is accusing Hims of “mass compounding,” suggesting that its compounded products aren’t made for specific patients. Compounded drugs offer telehealth companies higher margins than branded or generic.

When the partnership was announced in April, a Novo executive said the drugmaker and Hims were “developing a road map that combines Novo Nordisk’s innovative medications with Hims & Hers’ ability to deliver access to quality care at scale.” That aligns with Hims’ broader expansion vision. Novo did not respond to multiple requests for clarification on the nature of that collaboration.

Earlier this month, Lucas Montarce, Eli Lilly’s chief financial officer, said a provision in the company’s partnerships with telehealth providers is that they don’t compound either tirzepatide or semaglutide, the scientific names for Zepbound (Lilly’s weight-loss shot) and Wegovy. That confused industry onlookers because at least two of its partners appear to continue selling compounded versions.

Notably, Novo called off the partnership with Hims less than a week after it scored a legal win solidifying the Food and Drug Administration’s removal of semaglutide from its shortage list. The removal was challenged by a compounding pharmacy trade group that said the FDA ignored signs the drug was still in short supply. 

On June 17, the judge sided with the drugmaker, cementing the end of the shortage and Novo’s sole ability to mass produce semaglutide. (The trade group, Outsourcing Facilities Association, filed an appeal.)

Luke Kawa contributed to this article.

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‘Golden age of profit margins’ seen in 2026

Wall Street tends to be a pretty optimistic place. But on one measure, market watchers are the most optimistic on record.

FactSet data shows the consensus estimate for S&P 500 net profit margins in calendar year 2026 calls for the gauge to climb to 13.9% in 2026.

But if borne out by events next year “it will mark the highest (annual) net profit margin reported by the index since FactSet began tracking this metric in 2008,” wrote John Butters, senior earnings analyst at the financial data company.

A recent story from Barron’s also commented on the expectations for especially fat profit margins embedded into forecasts for next year.

“We are in the golden age of margins,” RBC’s Capital Markets’ head of US equity strategy, Lori Calvasina, told the magazine.

That’s good news for investors looking forward to next year. But the follow up question, of course, is where the growth in profitability is expected to come from. The answer, as you might have guessed, is tech. Though the precise mechanisms by which those profits land in the coffers of the giant tech firms remains something of a mystery. Barron’s doesn’t get into the details, saying “call it benefits from AI, pricing power, or whatever.”

That doesn’t exactly sound like money in the bank. But even die-hard haters of AI have to acknowledge that betting against the ability of giant tech companies to generate massive profit growth has been a bad trade for the last couple decades.

But if borne out by events next year “it will mark the highest (annual) net profit margin reported by the index since FactSet began tracking this metric in 2008,” wrote John Butters, senior earnings analyst at the financial data company.

A recent story from Barron’s also commented on the expectations for especially fat profit margins embedded into forecasts for next year.

“We are in the golden age of margins,” RBC’s Capital Markets’ head of US equity strategy, Lori Calvasina, told the magazine.

That’s good news for investors looking forward to next year. But the follow up question, of course, is where the growth in profitability is expected to come from. The answer, as you might have guessed, is tech. Though the precise mechanisms by which those profits land in the coffers of the giant tech firms remains something of a mystery. Barron’s doesn’t get into the details, saying “call it benefits from AI, pricing power, or whatever.”

That doesn’t exactly sound like money in the bank. But even die-hard haters of AI have to acknowledge that betting against the ability of giant tech companies to generate massive profit growth has been a bad trade for the last couple decades.

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Opendoor rises after CEO Kaz Nejatian touts an explosion in its home-buying footprint

Opendoor Technologies gained in early trading after CEO Kaz Nejatian touted an explosion in the company’s home-buying footprint.

In a message on X, the former Shopify COO posted two maps: one of which depicts a fairly limited area in which the online real estate company would buy or sell homes, and the second of which suggests that has now expanded to include the entire lower 48:

In a follow-up tweet, Nejatian attributed the gains to AI, writing, “First pic took 10 *years* of work without AI. Second pic took 10 *weeks* of work with AI.”

On his first earnings call as CEO, Nejatian said the company had adopted a “default to AI approach.”

One of his first pledges was to launch Opendoor everywhere in the lower 48.

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Hertz surges on bullish options activity

As millions begrudgingly make their way to the rental car counter amid the winter holidays, investors are pouring into calls and sending Hertz stock soaring.

As of 10:51 a.m. eastern, Hertz had seen 17,861 calls traded. That’s already significantly ahead of the 20-day average volume of 12,956. Hertz shares are up more than 12%.

Seemingly juicing the rally was a post on X that read “car rental companies could end up being the picks and shovels of autonomy” that was reposted by billionaire Bill Ackman, whose hedge fund is one of Hertz’s largest shareholders.

If Hertz’s price action holds, the move will mark its ninth-best trading day of 2025.

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POET Technologies jumps on elevated call activity

Optical communications company POET Technologies is up double digits in early trading on Monday as this potential supporting player in the AI boom gets a bid from the options market.

Just an hour after the opening bell sounded, call volumes are already running well above their five-session average for a full day.

The stock became a retail favorite in early Q4 right before many speculative trades began to retreat, with record call volumes of nearly 600,000 on October 7. The last big bump in options activity came on December 3, the session after Marvell’s acquisition of Celestial AI, a customer of POET, offered some validation for its technology as a data center solution.

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